I've probably sunk more hours into Fallout 4 than any other game, not only because it's a great game but also because of the OST by Inon Zur.
The title theme for Fallout 4 is also used by the recent Fallout TV series.
Most of the tracks are pretty subdued while filled withy variety, which make them a perfect backdrop for endless wandering and looting the wasteland.
While the sixty tracks make for a great backdrop during work etc, the best way to enjoy them is to play the game of course.